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[Google Scholar] Stat3 inhibitor Opb-51602 is cytotoxic to tumor cells through inhibition of complex I and ROS induction
These include personal or family history of medullary thyroid cancer, multiple endocrine neoplasia syndrome, or severe gastrointestinal conditions
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R Met/Met individuals have higher synaptic dopamine and norepinephrine (because COMT clears them more slowly), which improves prefrontal cortex function and working memory but increases susceptibility to stress-related anxiety, pain sensitivity, and catechol estrogen accumulation
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