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As a decomposition product, fatty acids, labelled as CO 2 , were measured in the air exhaled by the participants

The STEP 1 trial reported that once-weekly semaglutide led to a mean weight reduction of nearly 15% over 68 weeks in nondiabetic patients. Similarly, the SURMOUNT-1 trial of tirzepatide demonstrated weight loss exceeding 20% in some participants. Beyond weight loss, GLP-1s can have cardiovascular benefits, including reductions in blood pressure, improved lipid profiles, and decreased inflammation