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PMID 3257264
With an impaired immune system, the liver will become depleted from B12 reserves very rapidly
These inflammatory mediators can cross the BBB and activate microglia, the resident immune cells of the brain, leading to a chronic neuroinflammatory state that is strongly implicated in mood disorders and neurodegenerative conditions [148, 149]
For semaglutide specifically, cessation is advised at least 2 months before a planned pregnancy due to its long half-life
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