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In comparison, tirzepatide's best results were found in a phase 3 trial that showed the drug could lead to a weight loss of up to 20.9% at 72 weeks about 52 pounds for someone starting at 250 pounds
Bottom Line The peptide craze is unfounded
(PubMed) Ipamorelin is a growth hormone secretagogue (ghrelin receptor agonist class) designed to stimulate GH release with relative selectivity (less spillover into some other pituitary hormones compared with earlier compounds, based on early pharmacology literature)
persistent gastrointestinal symptoms beyond 2 weeks after discontinuation
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