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As an additional analysis, changes in weight and HbA1c, including the composite weight and HbA1c outcomes, were compared over the follow-up period in the following patient subgroups: persistentpatients who were persistent to the index therapy (defined as patients with 60 days gap in supply)
In head-to-head trials, tirzepatide 15mg vs semaglutide 1mg in type 2 diabetes showed greater A1c drop (~2.0% vs 1.4%) and greater weight loss (~11 kg vs 5 kg) ( [138] )
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