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The outer mitochondrial membrane is relatively permeable, but the inner mitochondrial membrane is strictly impermeable to long-chain fatty acids

Women (10%) are significantly more likely to experience binge eating than men (6%)

This 10-day early to mid-gestational window was selected to overlap rapid corticogenesis and the onset of synaptogenesis, modeling period-specific vulnerability rather than continuous stress across pregnancy

By building on a modeling framework previously assessed and validated within the Japanese CEA context, the analysis maintains methodological consistency with national evaluation standards while filling a major gap in prior assessments