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January 2026: Amgen completed Phase 3 enrollment for MariTide (AMG 133) in the MARITIME-Obesity trial, with interim efficacy data expected in Q3 2026 that will position the monthly injection GLP-1/GIP antagonist as a once-monthly obesity treatment alternative

Both saline- and GHRP-6-treated groups exhibited significant body weight loss compared to healthy sentinel rats, indicating that GHRP-6 did not prevent the cachectic weight loss induced by Dox

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The theoretical synergies described are based on component mechanisms rather than validated combination studies