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Observational studies have shown that GIP receptor mutations lead to decreased receptor signaling, which results in lower BMD and increased risk of fractures [50]
Step 3: Optimization phase (weeks 3-8) Based on assessment results, establish your working protocol: Dose: Your minimum effective dose (typically 75-200mcg) Frequency: 3-5 times weekly based on tolerance observations Timing: Your optimal pre-bedtime window Track results weekly and make minor adjustments as needed
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