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Pramlintide (Symlin) is the short-acting amylin analog FDA-approved 2005 for adjunctive use with insulin in type 1 and insulin-treated type 2 diabetes

Notably, a similar phenomenon was observed in neurons from patients with MS, characterized by upregulated STING expression and markedly reduced STIM1 expression, suggesting that STIM1-STING-GPX4 axis-mediated ferroptosis is closely associated with neuronal injury in human MS pathology (Woo et al., 2024)

Initially used for hydration and medication delivery in the early 20th century, IV therapy expanded its role in emergency medicine and surgery during the 1950s and 1960s