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In patients with MASLD and established CVD, GLP-1-based therapies are strongly supported as a cornerstone treatment addressing both hepatic and cardiometabolic disease burden simultaneously
Unique to retatrutide: dysesthesia Here is where retatrutide diverges from the other two
declares that he is a member of the Merck advisory board and has received honoraria for speaking from Sandoz, Merck-Serono, Pfizer, Versartis, Eli Lilly, Novo Nordisk and JCR
Future investigations employing sequential single-cell transcriptomics, specific inducible gene knockouts, and clinical cohort stratification are urgently needed to elucidate these temporal dependencies, which will pave the way for precise, stage-targeted RCD-modulating therapies in DKD
