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A GLP-1R agonist (liraglutide) increased endothelial nitric oxide synthase phosphorylation and nitric oxide (NO) production by the 5-AMP-activated protein kinase (AMPK)-dependent pathway and subsequent NO production in cultured HCAEC [56],[57]
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But crucially, 99.5 percent of GI events were non-serious, and 98.1 percent were mild to moderate
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