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The loss of skin elasticity (its ability to bounce back) combined with normal facial expressions causes wrinkles to gradually develop around the eyes
Lifestyle changes are essential but insufficient for most people
Underexplored peptide systems are highlighted to illustrate points of convergence with established incretin pathways rather than isolation from them
This accumulation reflects not only metabolic dysfunction and oxidative stress but also suggests a broader systemic disruption that may contribute to the pathogenesis of various age-related disorders, including central nervous system diseases [59]
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