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Hdac6-selective inhibitor overcomes bortezomib resistance in multiple myeloma
GH secretagogues, GHRH analogues and somatotropic axis modulators compounds validated for preclinical research The somatotropic axishypothalamus, pituitary gland, liveris the central regulator of muscle growth, protein synthesis, and body composition
Cell-intrinsic mechanisms underlie aging-dependent failure in the HSC niche 68 , including reduced regenerative capacity and an age-dependent increase in genes involved in the myeloid versus lymphoid lineage fate
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