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MACE was defined as the composite of CV death, nonfatal myocardial infarction, and nonfatal stroke
Ongoing monitoring should include regular review of weight loss progress, tolerability of side effects, and any changes in digestive symptoms
Supplements can affect oxidative stress markers, including glutathione levels
Nissen, who serves as study co-chair of SURMOUNT-MMO, notes that the exclusion of patients with diabetes will avoid confounding of results by favorable outcomes due to tirzepatides antidiabetic effects
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