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Human data is still very limited, including small pilot work such as the knee pain survey of 16 patients, plus a few other early studies and reviews calling out the lack of large, rigorous trials
Maybe the most damning finding here: FDA investigators directly observed study personnel retroactively completing records for an ongoing subacute systemic toxicity study , documenting "clinical observations and animal weight data from Day 1 of the study up to Day 26" all at once
Each option is designed for comfort, control, and clinical-grade performance
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