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While the peptide demonstrated a favorable safety profile, its development as a prescription obesity medication was discontinued in 2007 after mixed efficacy results in larger trials
While generally well-tolerated, some individuals may experience side effects such as: Irritation or redness at the injection site Temporary fatigue or nausea Immediate medical consultation is recommended if you experience severe side effects or allergic reactions
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Blocking NNMT is expected to raise SAM availability, but SAM participates in many cellular processes, so research must establish that selectively raising it does not perturb other methylation pathways
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