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In non-diabetic mice, GLP-1 infusion increased GFR by reducing preglomerular resistance [20], an observation that could potentially explain the physiological increase in GFR observed in the postprandial compared to the fasting state, although human studies infusing GLP-1 peptide could not replicate this observation [21]
This pathway plays a critical role in how the brain assigns value to rewarding experiences, including high-calorie foods
PMID 39817343
however, it declines with age [ 18 ]
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