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This oral preparation would offer a more convenient and comfortable option for patients, potentially leading to better treatment compliance.58,59 Overall, the future research direction of GLP-1RAs involves making them more similar to those in the human body, extending their duration of action, and creating oral formulations for easier administration.60,61 These advancements aim to improve patient experience, compliance, and treatment outcomes
After four half-lives (20 days), roughly 6% remains
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