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Improvements in access will take time, and require generation of compelling data (e.g., pharmacoeconomics, impact on comorbidities) and savvy commercial strategy

Its main manifestations include disorders of emotion, cognition, behavior, sleep, and appetite ( At present, less than half of the patients with depression are receiving effective treatments, with low cure rate and high recurrence rate ( This study mainly reviewed the literature on the determination of ACs in patients with depression or other mental illnesses

Effects are gradual and cumulative across multiple sessions

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