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In the liver, the accumulation of lipids is thought to impair mitochondrial function, thus reducing fatty acid oxidation and increasing the production of reactive oxygen species (ROS) that trigger lipid peroxidation, DNA damage, and apoptosis
2020;17:35 Rossi F, Lewis C
This results in reduced hunger and, for many patients, steady weight loss over time
Response varies with the severity and chronicity of the injury
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