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Future research should focus on integrating polygenic risk scores with environmental exposure metricssuch as long-term PM2.5 levels, radon, and occupational chemicalsto quantify cumulative disease risk

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Melatonin could resolve hyper-inflammatory conditions in COVID-19 and PASC by down-regulating proinflammatory cytokines (i.e., TNF-, IL-1, IL-6, and IL-8) and increasing anti-inflammatory cytokines such as IL-10 660,661

"Our findings...identify key characteristics that could inform the probability of achieving sustained weight loss of a magnitude large enough to provide clinically significant health benefits," Gasoyan told Newsweek