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We excluded symptomatic patients for this reason, focusing our investigation on asymptomatic individuals in whom risk assessment is less well defined

If you experience severe stomach pain, yellowing of the skin, or unusual changes in mood, seek immediate medical care

Elevated triglycerides can be a sign of insulin resistance, type 2 diabetes, low thyroid levels and metabolic syndrome, a constellation of conditions that are associated with insulin resistance, high blood pressure and too much fat around the waist

Additional safety concerns include hypoglycemia risk when used with insulin or insulin secretagogues, potential acute kidney injury with dehydration, and with semaglutide, worsening of diabetic retinopathy in patients with pre-existing retinopathy