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The main molecular mechanisms involved in the modulation of eryptosis studied to date, including intracellular calcium levels, ceramide, ROS, NO, changes in cellular energy metabolism, PS externalization, ion channel regulation, Fas-mediated signaling pathways, kinase-associated, and caspases activation, among others represent potential targets for inducing or inhibiting erythrocyte death
PTD-DBM topical spray applied daily for CXXC5 inhibition
Compared with control group, a visible increase of LDH levels was observed in Glu group
The 5-week-old female BALB/c nude mice were purchased from SLAC laboratory animals (Shanghai, China)
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