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Conversely, GLP-1RAs reduce inflammation in animals and humans with or without type 2 diabetes, independent of weight loss, with systemic anti-inflammatory actions evident within minutes to hours following acute administration of native GLP-1 [133] or GLP-1RAs [134,135,136]
In a diabetic kidney disease (DKD) model, liraglutide was demonstrated to enhance renal outcomes through the modulation of gut microbiota composition and the elevation of circulating levels of L-5-Oxoproline (5-OP)
The studies that are out there show that a high dose vitamin C is probably what is effective
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