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Surprisingly, a large number of GLP-1 users are reporting reduced use or total abstinence from substances like alcohol, cannabis, and nicotine

Because it is selective for the GLP-1 receptor, it functions in comparative work as the reference point against which dual and triple agonists are measured: an effect that semaglutide reproduces is a GLP-1-receptor effect, and an effect it does not reproduce is evidence that a second or third receptor is doing something

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Methionine may play a role in methylation-related processes that help regulate antioxidant defense and metabolic function