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Instruct patients to inform healthcare providers prior to any planned surgeries or procedures if they are taking Ozempic or Rybelsus tablets Adverse Reactions The most common adverse reactions (incidence 5%) are nausea, abdominal pain, diarrhea, decreased appetite, vomiting, and constipation Drug Interactions Semaglutide stimulates insulin release in the presence of elevated blood glucose concentrations

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In a 2026 study of 24 daily smokers, semaglutide lowered cigarette cravings and weight, but did not reduce the number of cigarettes smoked or change the main lab results

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