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Binding of GLP-1 to GLP1R has multiple effects, including enhancing insulin secretion from pancreatic beta cells in response to glucose, increasing insulin expression, preventing beta-cell apoptosis, promoting the formation of new beta cells, reducing glucagon secretion, slowing down stomach emptying, promoting satiety, and improving glucose disposal in peripheral tissues
Fontes-Dutra M, Santos-Terra J, Deckmann I, Brum Schwingel G, Della-Flora Nunes G, Hirsch MM, Bauer-Negrini G, Riesgo RS, Bambini-Jnior V, Hedin-Pereira C, Gottfried C
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