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It also alters melanin production from eumelanin (dark pigment) to phaeomelanin (lighter pigment), which contributes to its skin-brightening effect.(2) This mechanism explains why its often promoted as a depigmenting agent for issues like melasma, sun spots, and post-inflammatory hyperpigmentation
In preclinical studies, Ipamorelin has demonstrated minimal effects on cortisol, prolactin, and aldosterone levels at GH-stimulating concentrations, making it a cleaner research tool for isolating GH-specific effects
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