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Accessed January 2026
Nausea, constipation, diarrhea, bloating, and reduced appetite are frequently reported, especially during dose increases
PSI, also known as plastocyanin (Pc)/ferredoxin (Fd)-oxidoreductase, receives electrons from the mobile carrier Pc (transferring electrons from the Cyt b 6 f complex) and donates them to Fd, the terminal electron acceptor of the Z-scheme, which then reduces Fd-dependent NADPH reductase (FNR) (Stirbet et al., 2019)
Under metabolic stress, MOTS-c translocates from the cytoplasm to the nucleus, directly regulating gene expression related to stress adaptation
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