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While most population-relevant exclusions are not population-specific in their wording, the higher prevalence of hepatic steatosis reported in some Asian subgroups, combined with the very high prevalence of severe-hepatic-impairment exclusion criteria (50.3% of trials), may exert differential impact in practice (S5 Table)
For ADHD patients who experience afternoon anxiety or elevated resting heart rate on Vyvanse, a modest cortisol reduction could be subjectively helpful
Lifestyle changes: If your main concern is muscle loss or energy rather than fat loss, resistance training combined with adequate protein intake remains the most evidence-backed approach
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