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Vitamin D and molecular actions on the immune system: modulation of innate and autoimmunity
Patients were required to have exercise limitation and high symptom severity due to HFpEF reflected by a 6MWD of 100425 m and a KCCQ-CSS 80 at baseline, along with objective evidence of HF, as demonstrated by at least one of the following: (1) elevated NT-proBNP (200 pg ml 1 in sinus rhythm or 600 pg ml 1 in atrial fibrillation)
A vial manufactured 18 months ago and stored under unknown warehouse conditions may have significantly lower purity than a freshly manufactured batch, even if the CoA shows high purity at time of manufacture
Each batch is tested for purity, sequence accuracy, and quantity
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