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A 2025 meta-analysis in PMC (covering 36,754 tirzepatide and 106,057 semaglutide participants across multiple studies) confirmed tirzepatides advantage, finding an average 4.23 percentage points greater weight loss with tirzepatide an effect that was both dose- and duration-dependent
Tolerability: For some users, semaglutide may cause fewer gastrointestinal side effects compared to Mounjaro
How should you report side effects, and when should you seek immediate medical attention
If you eat slowly and in smaller portions more frequently throughout the day, you may be able to avoid that too full feeling
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