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87,89,90 From a clinical perspective, the available evidence supports individualised prescribing based on the patients risk profile, gradual dose escalation, proactive patient counselling before treatment initiation, regular assessment for clinically relevant adverse events during therapy, and targeted monitoring for renal dysfunction, retinopathy, pancreatitis, gallbladder disease, and musculoskeletal health, where clinically indicated
Adopt lifestyle changes such as improved hygiene and dietary adjustments
Studies have indicated the potential of Polypodium extract in diminishing melasma pigmentation, including its recurrence, showcasing promising outcomes in clinical settings
doi: 10.1016/j.aju.2017.11.008 70 AliMMartinezMParekhN
