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Furthermore, the presence of PGP at the peptide's C-terminus might also modify its interactions with specific transporters or receptors on the BBB, potentially favoring its transport via receptor-mediated transcytosis
Fras, JP., Davies, MJ., Rosenstock, J., Prez Manghi, FC., Fernndez Land, L., Bergman, BK., Liu, B., Cui, X., Brown, K.(2021)
The step from 0.25 to 0.5 mg doubles your dose, which is the largest relative increase in the entire titration schedule
It belongs to a novel class of drugs known as triple receptor agonists, meaning it simultaneously activates three distinct hormone receptors: the glucagon-like peptide-1 (GLP-1) receptor, the glucose-dependent insulinotropic polypeptide (GIP) receptor, and the glucagon receptor
