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Its high affinity for IGF binding proteins allows it to act quickly at the injection site, stimulating hyperplasia and muscle cell proliferation in specific muscle groups
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Backed by Science: Understand its critical role
[4] Together, the obesity and diabetes trials give retatrutide the broadest Phase 2 metabolic dataset of the two compounds, and the program has extended into hepatic (liver-fat / MASLD) and cardiometabolic questions that reflect the glucagon arms biology
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