Cell 113:935944 Mubarakshina MM, Ivanov BN, Naydov IA, Hillier W, Badger MR, Krieger-Liszkay A (2010) Production and diffusion of chloroplastic H 2 O 2 and its implication to signalling
It is essential for various bodily functions, including: Neutralizing free radicals and lipid peroxides Supporting immune function Detoxifying harmful substances Regenerating other antioxidants such as vitamin C and E Glutathione disulfide (GSSG) plays a crucial role in cellular oxidative stress and detoxification by maintaining the balance between reduced glutathione (GSH) and GSSG, which is vital for cellular health
Once inside cells, glutathione binds to free radicals, heavy metals, and toxins, converting them into harmless compounds that are eliminated by the liver and kidneys
N-acetylcysteine (NAC) and GSH, with antioxidant properties, can scavenge ROS during ischemiareperfusion injury