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KIF12-associated impaired functional cell polarity may be the underlying cause

doi:10.1042/BJ20081386, PMID: 19061483 Cox AG, Winterbourn CC, Hampton MB (2009) Mitochondrial peroxiredoxin involvement in antioxidant defence and redox signalling

Since B12 helps with energy levels, patients are more motivated to continue their diets and exercise, more than those who are not receiving B12 injections

When in the reduced state, GSH is active and protects cells and DNA by neutralizing reactive oxygen species, such as naturally occurring peroxides and free radicals produced during metabolism that could otherwise damage cellular components