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Metformin , the first-line type 2 diabetes drug and an AMPK activator, has cognitive data that are observational and inconsistent, and it lowers BDNF, a growth factor the brain relies on and that exercise raises, which is a reason for caution in a healthy brain
Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products
J.RomeroO.Insomnia Study Group of the Spanish Sleep Society SES (2022)
My scalp would get irritated and flaky, especially during those dry Calgary winters
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