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BMI 27 : Must also have prediabetes or a history of heart attack, stroke, or blocked arteries

Yet, the interplay between smoking and alcohol in the context of liver injury is increasingly recognized as a critical area of study

Monitoring schedule Healthcare providers who specialize in GLP-1 therapy typically recommend this monitoring cadence: Baseline: Full B12 panel before starting semaglutide 3 months: Repeat serum B12 and MMA 6 months: Full panel reassessment Annually: Once stable, annual monitoring is usually sufficient For high-risk patients (metformin users, vegans, those over 60, post-bariatric surgery), the 3-month check is particularly important

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