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Reductions in glutathione synthesis and tissue glutathione concentrations in aged animals (compared to younger ones) are suggestive of a potentially lower ability to respond to oxidative stress or toxin exposure (28)
The peptides small size and charge profile allow it to penetrate the stratum corneum, though penetration efficiency depends heavily on the vehicle
Worth DP, Davison AM, Lewins AM, Ledgerwood MJ, Taylor A
Disruption of these barriers can not only lead to severe pathology but also hinder the delivery of therapeutic agents to the CNS
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