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The most commonly studied agents in this context are semaglutide and liraglutide
6.0%), and 20% (14.3% vs 1.7%).The STEP 8 trial [157] (ClinicalTrials.gov identifier: NCT04074161) was a 68-week, randomized, placebo-controlled trial of either once-weekly semaglutide 2.4 mg, or once-daily liraglutide 3.0 mg, or placebo in adults with obesity or overweight with type 2 diabetes
Some may take a bit longer, particularly if their dose increases are faster or their digestive system is more sensitive
This is because GLP-1 agonists can help counteract the physiological causes of weight regain, which can help reduce yo-yo weight cycling over time, Mitri adds
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