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It is important to attend all follow-up appointments and to report any new or worsening symptoms promptly

Those are just a few and there are likely quite a few more to come

The primary site of action of loop diuretics is the Na + /K + /2 Cl cotransporter 2 (NKCC2: encoded by the SLC12A1 gene) which is present in the apical membrane of the epithelial cells in this region of the nephron