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Is the oral route possible for peptide and protein drug delivery
This accumulation is mediated by plasmalemmal transporters predominantly expressed in glial cell, such as divalent metal transporter 1 DMT1/SLC11A2 or zinc transporter ZIP14/SLC39A14, 374,375 which both transport Fe 2+ (ferrous), whereas Fe 3+ (ferric) is accumulated through transferrin receptors
But lyophilized peptide is not immune to degradation
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