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In summary, EE induced similar phosphorylation patterns of AKT and mTOR, P70S6K, and ERK pathway to that induced by IGF-1 during a 2-h time course, albeit to a less extent in AKT phosphorylation
Additionally, the utilization of UDE containing 1000 M -EC resulted in a negative impact on cell viability, whereas treatment with 1000 M -EC alone did not exhibit any toxic effects
As per this research, the primary treatment method is supplementation with vitamin B12
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