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Additionally, nearly half of the participants lost 30 percent or more of their body weight, a threshold long associated with surgical interventions rather than weight-loss medications

The GLP-1 pills are tablets you swallow, while the injectable versions are given with a syringe, usually in the upper arm, thigh, or abdomen (the belly area)

News-Medical+3EurekAlert!+3ASMBS+3 To put numbers on it: Surgical patients lost ~58 lbs in two years ( 24% of total body weight, or TBW) GLP-1 patients lost only ~12 lbs ( 4.7% TBW) over the same period EurekAlert!+2News-Medical+2 Even among GLP-1 users who continued therapy for a full year, weight loss averaged only ~7% TBWstill far less than surgical outcomes EurekAlert!+2ASMBS+2 Another rigorous analysis published in JAMA Surgery compared weight loss surgery and GLP-1 receptor agonists over two years

[PMID: 8611505] PubMed record related to this compound for laboratory literature review