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The dose of SFN administered was titrated down and 5mg/kg SFN was found to be sufficient to significantly prolong the survival of artesunate-treated mice infected with 1804 M488I parasites (Fig 8D-E)

By juxtaposing these next-generation therapies against conventional approaches, their significance not only lies in their innovative mechanism of action but also in their ability to provide hope for millions struggling with obesity and its associated comorbidities

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