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Month 2 (Weeks 5 through 8): This is the survival phase
A meta-analysis of 42,920 participants from five randomized trials demonstrated that GLP-1 RAs are associated with a significant reduction in the risk of the composite cardiovascular disease in patients with diabetes and established ASCVD [53]
Transient increases in the mean pulse rate of 1.1 to 4.6 beats per minute were observed during the trial
If adverse effects occur, NICE advises delaying an increase until they have resolved or become tolerable
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