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Furthermore, it has recently been reported that the induction of endoplasmic reticulum (ER) stress response, lens epithelial cell (LEC) apoptosis, and epithelial-mesenchymal transition (EMT) are implicated in the development of diabetic cataracts 15,16,17

It takes months to gradually increase the dose to the most effective level, and over a year for average weight loss to maximize in clinical trials

While semaglutide mimics hormones that regulate hunger and satiety, Topamax influences the nervous system, resulting in a more indirect effect on cravings and appetite. Note: Please do not stop taking Topamax without consulting your doctor and under medical supervision

Common early side effects include nausea, reduced appetite, and gastrointestinal discomfort, which usually diminish as the body adapts