doi: 10.3389/fpsyt.2025.1569826 Received 01 February 2025 Accepted 16 July 2025 Published 19 August 2025 Volume 16 - 2025 Edited by Sandra Moreno, Roma Tre University, Italy Reviewed by Poonam Chanderlal Sharma, University of Mississippi Medical Center, United States Ashish Patil, Roche, United States Updates Copyright 2025 Han, Almeida, Anand, Salloum, Kanaan, Gadad and Daher
Hepatic caspase-3 activity was measured utilizing a colorimetric assay kit purchased from Sigma Aldrich (MO, United States)
Thus, the biological control of intracellular GSH homeostasis through consumption and supply is an intricately balanced process that prevents oxidative stress
Cortistatin offers mechanistic clarity -- a well-defined receptor pharmacology, a specific mechanism of cortical synchronization, and validated homeostatic sleep factor properties -- but is limited to preclinical research with no human data and an impractical administration route