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Patients should be monitored for any exacerbation of gastrointestinal symptoms when using both medications concurrently

This could relate to different pharmacokinetic profiles, lower peak drug levels, or differences in how the oral versus injectable forms interact with the nervous system

Novo Nordisk A/S: Oral semaglutide 50 mg achieved 15.1% weight loss (17.4% if all people adhered to treatment) in adults with obesity or overweight in the OASIS 1 trial